Abstract: [
Abstract ] Objective Toevaluatetheeffectofparenteralnutritioncontainingfishoilfat
emulsiononadultcriticallyillpatients.Methods Studieswereidentifiedby Wanfang , CNKI ,
TheCochraneLibrary ( CochraneCentralRegisterofControlled Trials ), pubmedsearchfor
originalarticles.AccordingtotheinclusioncriteriaandJadad , dataoftheincludedstudieswere
extracted , andthe methodologicalquality wasevaluated.Then Meta-analysiswasperformed
usingRevMan5.1.Results Atotalof28RCTsinvolving1444patientsincluding9highquality
trials wereincluded.Meta-analysis showed that compared with controlled group , Acute
PhysiologyandChronicHealthEvaluation ( APACHE ) Ⅱscore [ SMD=-0. 55 , 95% CI ( -0. 76 ,
-0. 34 ), P <0.00001 , I
2 =14% ], LengthofICU stay [
SMD= -1. 06 , 95% CI ( -1. 43 ,
-0. 70 ), P <0.00001 , I
2 =84% ] andinfectiouscomplications [
OR =0.42 , 95% CI ( 0.28 ,
0.65 ), P <0.0001 , I
2 =0% ]
hadsignificantdifferences.Buttherewerenosignificantdifference
in28-d mortality [ OR =0.59 , 95% CI ( 0.32 , 1.10 ), P =0.10 , I
2 =0% ]
.Conclusion The
parenteralnutritioncontainingfishoilfatemulsioncanpartlyimprovetheconditionsofcritically llpatients , butdidnotaffecttherecentprognosis.

Key words: parenteralnutrition , fishoils , Meta-analysis