Abstract: ［Abstract］ Objective〖HTSS〗〓To investigate the diagnostic efficiency of differences in corrected coronary opacification(CCO) measured with computed tomography combined with biochemical indexes for coronary heart disease.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓The 205 patients whose left anterior descending artery stenosis rate were greater than 70%, were divided into two groups, 119 patients ≥70%, 86  patients<70%. All patients were detected with the following parameters: three glycerol(TG), total bilirubin(TBIL), gamma glutamyl transferase(GGT), total cholesterol(TC), high density lipoprotein cholesterol(HDLC), uric acid(UA), glycosylated hemoglobin(HbA1c), low density lipoprotein cholesterol(LDLC), apolipoprotein A(APOA), apolipoprotein B(APOB), Lp(a), homocysteine(Hcy). All patients were treated by CT workstation image postprocessing, the differences in CCO before and after the left anterior descending branch stenosis was measured. The Logistic regression analysis and the ROC curve were used to screen the indexes closely related to coronary heart disease, and the differences in CCO.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓The difference of the biochemical indexes of the two groups was statistically significant(P＜005). Multivariate Logistic regression analysis showed that UA, GGT, Hcy, APOB, Lp (a) were independent risk factor. The stenosis rate was higher than 70%, the ROC curve is selected from the CCO, GGT, APOB. The difference of 3 indexes of AUC>0.750. The sensitivity of difference in CCO combined with GGT and APOB was 0.924, and the specificity was 0.651.
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓Differences in CCO combined with GGT and APOB enhanced the sensitivity to reduce the specificity, and could significantly improve the diagnostic efficiency of the coronary stenosis rate.

Key words: coronary stenosis, tomography, spiral computed, diagnosis