Journal of Hebei Medical University

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Effect of PKRP on prostate function and serum prostate specific antigen level in patients with BPH#br#

  

  1. 1.Department  of  Uropoiesis Surgical, Yan′an People′s Hospital, Shaanxi Province, Yan′an
    716000, China; 2.Department  of  Uropoiesis Surgical, Yan′an University Affiliated
    Hospital, Shaanxi Province, Yan′an 716000, China
  • Online:2018-08-25 Published:2018-07-25

Abstract: [Abstract] Objective〖HTSS〗〓To explore the effect of plasma kinetic resection of prostate(PKRP) on prostate function and serum prostate specific antigen level in patients with benign prostatic hyperplasia(BPH).
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓The 120 patients with BPH were selected and randomly divided into experimental group and control group. The experimental group was performed transurethral plasma kinetic resection of prostate, while the control group was treated with transurethral resection of prostate. The urethral function and sexual function were compared between the two groups before and after treatment: Urethral function included maximum urinary flow rate(Qmax), residual urine volume, maximum bladder volume and bladder pressure at the beginning of voiding; Sexual function included the International Index of Erectile Function5(IIEF5) and the proportion of people with retrograde ejaculation. Serum prostate specific antigen(PSA) levels were compared between the two groups before and after treatment.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓After treatment, the Qmax in the experimental group was significantly higher than that in the control group, the residual urine volume and urinary bladder pressure at the beginning of urination were significantly lower than those in the control group(P<005). After treatment, the IIEF5 score of the experimental group was significantly higher than that of the control group, the number of erectile dysfunction and the number of retrograde ejaculation was significantly lower than that of the control group(P<005). After treatment, the PSA of two groups was first increased and then decreased. The observation group was lower than the control group. The differences between the two groups were statistically significant(P<005).
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓PKRP can effectively improve the postoperative urethral function and sexual function in patients with BPH, and 28 days after operation, the level of PSA in patients returned to normal. It is worthy of clinical application.

Key words: prostatic hyperplasia, transurethral resection of prostate, prostate specific antigen