Abstract: ［Abstract］〓Objective〖HTSS〗〓To evaluate the role of MRI and cerebrospinal fluid examination in the diagnosis of intracranial tuberculosis, to explore the difficulties in the diagnosis of intracranial tuberculosis, and to clarify the diagnostic ideas.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓The clinical data of 71 patients with intracranial tuberculosis were retrospectively analyzed. The results of MRI and cerebrospinal fluid examination were analyzed.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓The results of MRI showed that 32 cases had abnormal brain parenchyma, 28 cases had abnormal brain parenchyma and meninges at the same time; only 4 cases had typical changes of cerebrospinal fluid in tuberculous meningitis, 7 cases had atypical changes of cerebrospinal fluid, and 4 cases had simple increase of intracranial pressure. The results of cerebrospinal fluid examination showed that 12 cases of tuberculosis were detected by modified acidfast staining of cerebrospinal fluid, 31 cases were positive for cerebrospinal fluid tuberculosis culture, 27 cases were intracranial hypertension, 49 cases were increased in cerebrospinal fluid routine cells, 35 cases were increased in cerebrospinal fluid protein, 39 cases were decreased in cerebrospinal fluid sugar, 42 cases were decreased in chloride and 39 cases were increased in adenosine deaminase. There were 71 cases of intracranial tuberculosis, 60 cases(84.5%) were positive by MRI, 54 cases(76.0%) were positive by cerebrospinal fluid examination. There was no significant difference in the positive rate between the two methods(P＞005), and the Kappa value was -0.232, suggesting that the consistency of the two methods was not good and each method had advantages.
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓Brain magnetic resonance plain scan plus enhanced scan and cerebrospinal fluid examination play an irreplaceable role in the diagnosis of intracranial tuberculosis. Each has its own advantages. When clinical suspected cases of intracranial tuberculosis and cerebrospinal fluid bacteriological examination is negative, the detection rate of intracranial tuberculosis should be improved by plain scan plus enhanced combined with cytological and biochemical examination of cerebrospinal fluid.

Key words: intracranial tuberculosis, magnetic resonance imaging, cerebrospinal fluid examination