Abstract: ［Abstract］〓Objective〖HTSS〗〓To investigate the clinical effects of carprostol tromethamine in patients with postpartum hemorrhage and the effects on fibrinogen(FIB) and Ddimer(DD) levels.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓A total of 78 patients with postpartum hemorrhage were enrolled. The patients were randomly divided into study group and control group by weighting method, with 39 cases in each group. The control group was treated with oxytocin, and the study group was treated with carprost tromethamine. The therapeutic effects, FIB and DD levels, postpartum hemorrhage, duration of lochia, rate of decline of the uterus, and uterine contraction time were compared between the two groups.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓The therapeutic effect of the study group is better than that of the control group(P＜005). After treatment, the levels of FIB and DD in the two groups were lower than those before treatment, and the levels of FIB and DD in the study group were lower than those in the control group(P＜005). The bleeding volume of the study group at 1 h and 12 h after birth was less than that of the control group. The uterine contraction time was longer than that of the control group. The uterus bottom decreased faster than the control group, and the duration of lochia was shorter than that of the control group(P＜005).
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓Carbaryl tromethamine is effective in the treatment of postpartum hemorrhage, which improves clinical symptoms, reduces the level of FIB and DD, improves the quality of life, and has higher safety, which can be widely applied in clinical practice.

Key words: postpartum hemorrhage, carprostol tromethamine, fibrinogen, Ddimer