Abstract: ［Abstract］Objective〖HTSS〗To analyze the risk factors of human papilloma virus (HPV) genotypes in patients with cervical cancer.
〖HTH〗〖WTHZ〗Methods〖HTSS〗A total of 322 women diagnosed as cervical cancer were tested for HPV genotyping and investigated by epidemiological questionnaire. Meanwhile, the main influencing factors of different HPV genotypes were analyzed by multiple factor regression method to find out the high risk factors.
〖HTH〗〖WTHZ〗Results〖HTSS〗Among 322 women surveyed, 23 subtypes of HPV were detected. The top three subtypes of HPV infection rate were HPV18, HPV16 and HPV53, accounting for 17.8%, 15.0% and 13.8% respectively. Univariate analysis of variance showed that the main risk factors affecting HPV18 infection were age, number of sexual partners and first intercourse(P＜0.05). The main risk factors affecting HPV16 infection were age, number of pregnancies, age of first sexual life(PP＜0.05). Age and number of pregnancies were risk factors for HPV53 infection(P＜0.05). The results of binary logistic regression analysis showed that age and number of sexual partners were independent risk factors for HPV18 infection. Age and number of pregnancies were independent risk factors for HPV16 infection. Number of pregnancies is independent risk factors for HPV53 infection(P＜0.05).
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗Age and number of sexual partners are related to HPV18 infection, age and number of pregnancies are related to HPV16，and number of pregnancies is related to HPV53 infection,so timely intervention should be given in daily education.