Abstract: Objective In order to analyze the correlation of the wings apart-like( Wapl ) protein and the synaptonemal complex( SC)of pachytene oocytes. Methods The pachytene oocytes were isolated from foetal mice ovaries at 18 . 5 d and double immunostained with anti-synaptonemal complex protein2( SYCP2 )and anti-Wapl. Results In the pachytene oocytes examined,mouse Wapl was colocalized with SYCP2 on the SC. Conclusion Wapl may be a part of pachytene oocyte SC.

Key words: zygote, synaptonemal complex, proteins, rats