Abstract: ［Abstract］ Objective〖HTSS〗〓The goal of this study was to investigate the effect on renal function in patients with coronary angiography or percutaneous coronary intervention(PCI)  after coronary CT angiography(CTA) within 1 week.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓A total of 384 patients underwent coronary angiography or angioplasty were enrolled into two groups:the test group 135 who were undergoing coronary angiography or angioplasty after coronary CTA within 1 week, and control group 249 who were undergoing coronary angiography only. Serum creatinine, cystatin C and the incidence of contrast induced nephropathy(CIN) were detected before procedure, after procedure 1 d, 2 d, 3 d.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓There was no significant difference in serum creatinine, estimated glomerular filtration rate(eGFR), and cystatin C between groups before and after contrast exposure(P＞005). But there was significatnt difference between different point(P＜001). The study resulted in 16 cases of CIN, and there was no significant difference in the incidence of CIN between two groups(4.44% vs 4.02%, P＞005). The difference of PCI between the two groups was statistically significant(P＜001), and the PCI procedure in test group was significantly higher than that in control group(54.07% vs 33.33%).
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓It is safe and feasible for patients with an eGFR≥60 mL·min-1·1.73 （m2)-1 to received coronary angiography or PCI after CTA within 1 week, and it has little impact on the renal function.

Key words: coronary artery disease, coronary angiography, contrast induced nephropathy