Abstract: ［Abstract］〓Objective〖HTSS〗〓To analyze the clinical effect of nasal continuous positive airway pressure(nCPAP) for prior ventilatory support strategy on severe pneumonia in infants.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓Seventy cases of severe pneumonia were randomly divided into control group and nCPAP treatment group,and each group with 35 cases. The control group was received oxygen with ordinary mask, while the nCPAP group received nCPAP prior treatment.Compared with two groups of treatment effect, partial pressure of oxygen(PaO2), partial pressure of carbon dioxide(PaCO2), PaO2/fraction of inspiration O2(FiO2) were compared before and after treatment 2h,24h,48h. The time of breathing difficulty relief and the rate of endotracheal intubation were compared too.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓The time of breathing difficulty relief was shortened,the rate of endotracheal intubation was reduced in nCPAP group, compared with control group. The differences were statistically significant(P＜005). After treatment, PaO2 and PaO2/FiO2 in two groups increased gradually, PaCO2 decreased gradually, PaO2 and PaO2/FiO2 in nCPAP group were higher than those in control group, PaCO2 was lower than those in control group. There were significant differences in the interaction among groups, time points and time points between groups(P＜005).
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓The application of nCPAP priority strategy in the treatment of Infantile Severe Pneumonia is effective. It can prevent the progress of the disease, reduce the rate of tracheal intubation. It is a noninvasive breathing support technology worth promoting.

Key words: pneumonia, continuous positive airway pressure, infants