Journal of Hebei Medical University

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Clinical significance of standardized operation in transcatheter contact thrombolysis of deep venous thrombosis of lower extremity#br#

  

  • Online:2019-12-25 Published:2019-12-26

Abstract: [Abstract] Objective〖HTSS〗To evaluate value of standard procedure in catheter-directed thrombolysis(CDT) for deep venous thrombosis(DVT) of lower extremity patients.
  〖WTHZ〗Methods〖HTSS〗A total of 276 louer extremity DVT patients treated with CDT in our hospital were analyzed retrospectively. One hundred and twenty-four DVT patients treated with CDT before standard procedure performed were defined as group A, 152 DVT patients treated with CDT after standard procedure performed were defined as group B. The incidence rate, complications were compared between two groups.
  〖WTHZ〗Results〖HTSS〗The incidence rate of group A was significantly higher than group B, 32.26%(40/124) vs 5.26%(8/152) (P<0.05). The most common problem of catheterization was catheter displacement. There were 21 cases(16.94%) in group A and 3 cases(3.29%) in group B(152 cases). The most serious misoperation was 1 case in group A whose thrombolysis catheter, anticoagulant micropump, vascular sheath triple connection, urokinase micropump were connected incorrectly, which directly led to thrombus growth along the catheter and the thrombolysis time prolonging.There was no major bleeding complication in group B, which was significantly lower than 10 cased(8.06%)of group A(P<0.05). The most serious complication was a case of group A who had early signs of cerebral hemorrhage, such as headache, dizziness.
  〖WTHZ〗Conclusion〖HTSS〗Standard procedure in CDT for DVT patients may lower incidence rate, prevent complications, improve clinic outcomes.

Key words: venous thrombosis; lower extremity, catheter-directed thrombosis, standardized operation