Journal of Hebei Medical University

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Therapeutic effect of repetitive transcranial magnetic stimulation therapy on common peroneal nerve injury

  

  1. 1.Department of Rehabilitation Medicine, the Second Hospital of Hebei Medical University,
    050000, China; 2.Department of Outpatient, the Army Engineering University of
    the People′s Liberation Army, Shijiazhuang 050000,China
  • Online:2020-04-25 Published:2020-05-15

Abstract: [Abstract]Objective〖HTSS〗To observe the effect of repetitive transcranial magnetic stimulation on the injury of common peroneal nerve, and to explore the effect on the expression of nerve growth factor(NGF) and basic fibroblast growth factor(bFGF).
 〖WTHZ〗Methods〖HTSS〗Eighty male normal healthy Prague Dawley New Zealand rabbits were randomly divided into treatment group and model group. The treatment group was given repeated transcranial magnetic stimulation. Electromyography and motor conduction velocity were examined before and after treatment. The expression of NGF and bFGF in the injured common peroneal nerve tissue of 80 rabbits was detected by streptavidin-perosidase(SP) method The results were tested and analyzed statistically.
 〖WTHZ〗Results〖HTSS〗After treatment, the number of abnormal indexes of insertion potential and prolonged fibrillation potential in the two groups was significantly less than that before treatment, and the number of abnormal indexes of motor unit potential was significantly more than that before treatment, the difference was statistically significant(P<0.05). After treatment, the number of abnormal indexes of insertion potential and prolonged fibrillation potential in the treatment group was significantly less than that in the model group, and the number of abnormal indexes of motor unit potential in the treatment group was significantly more than that in the model group(P<0.05). After treatment, the motor nerve conduction velocity and amplitude of the two groups were higher than before treatment, and the motor nerve conduction velocity and amplitude of the treatment group were higher than the model group, the difference was statistically significant(P<0.05). The gray values of NGF and bFGF in the injured peroneal nerve tissue of the treatment group were significantly higher than those of the model group(P<0.05).
 〖WTHZ〗Conclusion〖HTSS〗Repetitive transcranial magnetic stimulation therapy can effectively improve the lower limb motor function in patients with common peroneal nerve palsy. NGF and bFGF can promote the functional recovery after PNI, reconstruct the tissue structure of regenerated nerve, and play an important role in the repair ment of peripheral nerve injury.

Key words: peripheral nerve injury, repetitive transcranial magnetic stimulation, therapeutic effect