Abstract: Objective  To observe the clinical effect of active silver ion antibacterial liquid in the treatment of children's oral ulcer.
  Methods  A total of 92 children with oral ulceration were selected from our department. The children were divided into experimental group and control group according to the principle of random, and 46 cases in each group. The experimental group was given local treatment with active silver ion antibacterial liquid, while the control group was given local treatment with kangfuxin liquid. The treatment effect, the time of relieveing pain, the healing time of the ulceration, the degree of pain after treatment and the degree of response of the children to the drug were observed.
  Results  Compared with the control group, there was no significant difference in the overall effective rate of the experimental group(P＞0.05).  The pain relief time of oral ulcer in the experimental group was shorter than that in the control group, the difference was statistically significant(P＜0.05). There was no significant difference in healing time between two groups(P＞0.05). After treatment, the degree of pain in the experimental group was significantly lower than that in the control group, the difference was statistically significant(P＜0.05). The compliance of children in the experimental group to drug use was significantly better than that in the control group, the difference was statistically significant(P＜0.05).
  Conclusion  The active silver ion antibacterial liquid can promote the improvement of clinical symptoms, accelerate the healing of the ulceration, relieve the local pain of the child, and is more suitable for children, and has remarkable effect and is worthy of popularization and application.

Key words: Mouth ulcer, signs and symptoms, anti-bacterial agents