Abstract: Objective  To explore the influence of the construction and rectification of the green channel for thrombolysis in stroke on the time from onset to treatment time（OTT）, the door to needle time（DNT）, thrombolysis rate, clinical efficacy and prognosis of thrombolysis, and highlight the value of the construction and rectification of the green channel for stroke. 
Methods  The clinical data of 118 patients with thrombolytic therapy through green channel were collected and divided into control group(57 cases) and observation group(61 cases) according to time. The OTT, DNT, DNT≤60 min ratio, National Institute of Health stroke scale（NIHSS） score, significant efficiency, complications and Modified Rankin Scale（mRS） score were compared between two groups. 
Results  The OTT and DNT of observation group were shorter than those of control group, and the proportion of DNT≤60 min was higher than that of control group(P＜0.01). After 72 hours of thrombolytic therapy, the clinical efficacy of observation group was better than that of control group, and the total effective rate was higher than that of control group(P＜0.01). There was no significant difference in the incidence of complications and mortality between the two groups(P＞0.05). The NIHSS scores of the two groups were gradually decreased, and the NIHSS score of the observation group was lower than that of control group and the differences of interaction among groups, time points and time points between groups were statistically significant(P＜0.01). The BI scores of two groups were gradually increased, and the BI score of the observation group was higher than that of the control group. The differences of interaction between groups, time points and time points between groups were statistically significant(P＜0.01).After 3 months of treatment, the mRS score of observation group was significantly lower than that of control group, and the proportion of ≤ 2 points was higher than that of control group(P＜0.01). 
Conclusion  Through the establishment of the green channel for thrombolysis， the OTT and DNT can be significantly shortened, the thrombolysis rate and the efficacy of cerebral infarction can be improved, and the degree of disability can be reduced, thus achieving good social benefits.

Key words: stroke, thrombolytic green channel, quality improvement, treatment outcome