Abstract: Objective  To explore the related factors affecting recurrence in patients with central serous chorizoretinopathy(CSC).
Methods  A total of 90 patients with CSC admitted to our hospital were selected. All patients were hospitalized for fundus fluorescence angiography(FFA) and visual acuity examination. Patients were followed up for 6 months after treatment for visual function review and fundus angiography review. Patients were divided into a recurrent group(n=30) and a non-recurrent group(n=60) according to their recurrence.Univariate analysis and multivariate Logistic regression analysis were used to analyze the independent risk factors affecting CSC patients recurrence, and Spearman correlation analysis was used to analyze the correlation between risk factors and CSC recurrence. The area under the receiver operating characteristics(ROC) curve(AUC) was used to analyze the evaluation value of risk factors for CSC patients recurrence. 
Results  Univariate analysis showed that there were significant differences between two groups in course of disease, type of leakage, leakage area and distance of leakage points(P＜0.05). The results of multivariate Logistic regression analysis showed that course of disease, type of leakage, leakage area and distance of leakage points were independent risk factors for recurrence in CSC patients(P＜0.05). Spearman correlation analysis showed that the course of disease, type of leakage, leakage area and distance of leakage points were in a linearpositive correlation with CSC recurrence(P＜0.05). The specificity(89.87%), sensitivity(87.91%) and AUC(0.895) of the combined indicators of the course of disease, type of leakage, leakage area and distance of leakage points in CSC patients were significantly higher than those of the single indicator(P＜0.05). 
Conclusion  There are many related factors affecting CSC patients′ recurrence. The course of disease, type of leakage, leakage area and distance of leakage points are independent risk factors affecting CSC patients recurrence.

Key words: central serous chorizoretinopathy, recurrence, relative factors