关键词: 斑块, 动脉粥样硬化, 超声检查, CT血管显像

Abstract: ［Abstract］ Objective〖HTSS〗〓To compare and analyze the diagnostic value of carotid ultrasound, CT angiography(CTA) and  magnetic resonance imaging(MRI) in the diagnosis of carotid atherosclerosis plaque.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓The plaque tissues of 55 patients with carotid atherosclerosis plaque treated by carotid endarterectomy(CEA) were collected. Fiftyfive atherosclerosis plaques were routinely sliced by HE and immunohistochemical staining, labeling CD31, CD34 and FⅧ antibodies were used to analyze various components in the plaque and to determine plaque stability, and to classify the relevant pathological features of the plaque. At the same time, the results of preoperative carotid ultrasound, CTA and MRI on the plaque properties were collected from 55 patients, and the pathological diagnosis was compared with gold standard.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓There was no significant difference in the detection rate of vulnerable plaques between carotid ultrasound and pathology(P＞005). There was significant difference in the detection rate of vulnerable plaques between CTA and pathology(P＜005).There was no significant difference in the detection rate of vulnerable plaques between MRI and pathology(P＞005),and sensitivity of MRI＞carotid ultrasound＞CTA.
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓Carotid ultrasound and MRI can be used to evaluate the vulnerability of plaque in patients with carotid atherosclerosis plaque,and the sensitivity of MRI is higher.

Key words: plaque, atherosclerotic； ultrasonography, CT angiography