冠状动脉钙化积分对疑似心源性慢性胸痛患者心血管事件的预测意义

doi:10.3969/j.issn.10073205.2019.04.018

河北医科大学学报

冠状动脉钙化积分对疑似心源性慢性胸痛患者心血管事件的预测意义

1.河北省秦皇岛市第一医院 CT室，河北秦皇岛 066000；2.河北省秦皇岛市第一医院CCU，河北秦皇岛 066000

出版日期:2019-04-25 发布日期:2019-04-22
作者简介:王泽静（1982-），女，河北秦皇岛人，河北省秦皇岛市第一医院主治医师，医学硕士，从事医学影像诊断研究。

Prognostic value of coronary artery calcification in patients with suspected cardiogenic chronic chest pain#br#

1.Department of CT Room, the First Hospital of Qinhuangdao, Hebei Province, Qinhuangdao
066000, China； 2.Department of Coronary Care Unit, the First Hospital of Qinhuangdao,
Hebei Province, Qinhuangdao 066000, China

Online:2019-04-25 Published:2019-04-22

摘要/Abstract

摘要： ［摘要］〓
〖HTH〗目的〖HTSS〗〖KG*2〗应用多排螺旋CT研究疑似心源性慢性胸痛患者冠状动脉钙化(coronary artery calcification,CAC)积分对心血管事件的影响。
〖HTH〗方法〖HTSS〗〖KG*2〗序贯入选就诊的疑似心源性慢性胸痛患者101例，行64排螺旋CT扫描（非增强），计算CAC积分，依据CAC积分将患者分为CAC积分≤300分和CAC积分＞300分2组。观察随访1年，观察终点事件为急性心肌梗死、心源性死亡、因急性冠状动脉综合征再入院和血运重建。
〖HTH〗结果〖HTSS〗〖KG*2〗101例患者发生心血管事件13例，均为因急性冠状动脉综合征再入院，无心源性死亡和急性心肌梗死发生，其中CAC积分≤300分组发生4例，CAC积分＞300分组发生9例。CAC积分＞300分组糖尿病患病比例、总胆固醇水平均高于CAC积分≤300组，差异有统计学意义（P＜0.05）。应用Cox比例风险回归模型进行分析，结果显示CAC积分＞300分的HR值为4.616，95%CI为1.046~20.377，P=0.043。
〖HTH〗结论〖HTSS〗〖KG*2〗CAC积分＞300分是疑似心源性慢性胸痛患者发生心血管事件的危险因素。

关键词: 胸痛, 冠状动脉钙化积分, 心血管事件

Abstract: ［Abstract］〓Objective〖HTSS〗〓To evaluate the prognostic value of the coronary artery calcium(CAC) score in patients with suspected cardiogenic chronic chest pain.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓A total of 101 consecutive patients with suspected cardiogenic chronic chest pain were enrolled from our hospital. The CAC score was calculated and patients were divided into a lower CAC score group(CAC score≤300) and a higher CAC score group(CAC score>300). Patients were followed up for one years to assess adverse events consisting of a combined end point of cardiac death, myocardial infarction, coronary revascularisation, and returning to hospital for acute coronary syndrome(ACS).
〖HTH〗〖WTHZ〗Results〖HTSS〗〓During the observation period no patients died or suffered from myocardial infarction and 13 patients returned to the hospital for ACS. Among them, 4 cases occurred in the group with CAC score ≤300, and 9 cases occurred in the group with CAC score>300. The proportion of diabete and total cholesterol level of group with CAC score >300 were higher than that of the group with CAC score≤300, and the difference was statistically significant(P＜005). The Cox regression analysis results showed that the CAC score was a risk factor for the noevent survival time(HR=4.616; 95%CI=1.046-20.377, P=0.043).
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓CAC score>300 is a predictor of cardiac events for patients with suspected cardiogenic chronic chest pain.

Key words: chest pain, coronary artery calcification score, cardiovascular event

王泽静1，王〓询2，肖〓康1 . 冠状动脉钙化积分对疑似心源性慢性胸痛患者心血管事件的预测意义[J]. 河北医科大学学报, doi: 10.3969/j.issn.10073205.2019.04.018.

WANG Zejing1， WANG Xun2， XIAO Kang1. Prognostic value of coronary artery calcification in patients with suspected cardiogenic chronic chest pain#br#[J]. Journal of Hebei Medical University, doi: 10.3969/j.issn.10073205.2019.04.018.

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冠状动脉钙化积分对疑似心源性慢性胸痛患者心血管事件的预测意义

Prognostic value of coronary artery calcification in patients with suspected cardiogenic chronic chest pain#br#

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