澳泰乐治疗肠易激综合征临床观察及对家兔结肠影响的研究

›› 2001, Vol. 22 ›› Issue (2): 80-80.

澳泰乐治疗肠易激综合征临床观察及对家兔结肠影响的研究

赵辉;赵宏;梁惠宾

北京大学人民医院%河北医科大学第二医院%北京大学药学院

发布日期:2001-03-25

LIU Sucai;Yang Xuehui;LI En

Zhao Hui;Zhao Hong;LIANG Huibing

Published:2001-03-25

摘要/Abstract

摘要： 目的观察评价澳泰乐冲剂治疗肠易激综合征的价值和作用机制。方法①用澳泰乐冲剂治疗58例肠易激综合征患者2周，并与培菲康对照。②观察澳泰乐对被阿托品和氯化钡致痉的离体兔结肠的作用。结果①总有效率：澳泰乐组89.66 %，培菲康组 65 %（P<0.001）。②澳泰乐有效的缓解被阿托品和氯化钡致痉的离体兔结肠(P<0.001)。结论澳泰乐是治疗肠易激综合征的有效药物，其作用机理可能与抗结肠平滑肌受体和影响结肠离子通道有关。

关键词: 结肠疾病, 功能性/中医药疗法, 结肠疾病, 功能性/治疗, 澳泰乐

Abstract: Objective　To evaluate the clinical valuation and effect of Aotaile infusion on irritable bowel syndrome (IBS).Methods　Inverstigate the effect of 58 cases treated with Aotaile infusion for 2 weeks in comparing with the control group treated with Bifico and investigated to the effect of Aotaile on the spastic colon of rabbit was induced by acetylcholine and BaCl2. Results　The total effective rate by Aotaile infusion reached 89.66 % and by Bifico reached 65 % (P<0.001).Which was inverstigated to Aotaile markedly improved spastic colon of rabbit's was induced by acetylcholine and BaCl2 in vitr.Conclusion　It is one of the effective Chinese drugs for the treatment of IBS.

中图分类号:

R574.4

赵辉;赵宏;梁惠宾. 澳泰乐治疗肠易激综合征临床观察及对家兔结肠影响的研究[J]. , 2001, 22(2): 80-80.

Zhao Hui;Zhao Hong;LIANG Huibing. LIU Sucai;Yang Xuehui;LI En[J]. , 2001, 22(2): 80-80.

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