Abstract: ［Abstract］ Objective〖HTSS〗〓To evaluate the risk factors of the antibiotic resistance of Imipenem(IPM), Meropenem(MEM) and CefperazoneSulbactam(SCF) among the Acinetobacter baumannii(AB) pneumonia.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓A total of 944 specimens from lower respiratory tract with acinetobacter baumannii pneumonia were identified: 931, 712 and 887 were subjected to antimicrobial susceptibility testing in IPM, MPM and SCF, respectively. The difference in the rate of multidrugresistant Acinetobacter baumannii(MDRAB) and the clinical characteristics between the dichotomized resistant group and nonresistant group in the three antimicrobial susceptibility testing were analyzed, respectively. Then we used Logistic regression analysis to evaluate the risk factors.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓The MDRAB rates of the resistant group were  higher than the nonresistant group in the three antibacterial agents(P＜005). There were significant differences in sex, the use of invasive operation, urinary tract intubation, trachea cannula, tracheotomy, ventilator, central venous catheter, surgery, internal or surgical department, intensive care unit, times of hospitalization, hospital stays and season between the dichotomized resistant group and nonresistant group in IPM, MEM and SCF(P＜005). Logistic regression analysis suggested that the use of ventilator before delivery could increase the risk of these three antibioticresistance(P＜005). While ABpneumonia patients in men, intensive care unit, the antibioticusedays≥5 d and SpringWinter could be easily resistant to both IPM and MEM(P＜005). And  resistance to IPM may easily happened in surgical department and only one timehospitalization（P＜005）. 
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓he prevention and control measures should be designed according to the highrisk population, the highincidence season and the highoccurrence period of each kind of drugsensitive drug resistance, so as to shorten the time of antibiotic use, attach importance to the daily bacterial detection, improve the early detection rate at admission, and effectively control the occurrence and development of bacterial resistance to antibiotics.

Key words: Acinetobacter baumannii, lower respiratory tract infections; , multidrugresistant