Journal of Hebei Medical University

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Effect of probiotics on inflammatory response in patients with severe burns

  

  1. Department of Clinical Nutrition, the First Hospital of Hebei Medical University, Shijiazhuang 050031, China
  • Online:2019-12-25 Published:2019-12-26

Abstract: [Abstract]Objective〖HTSS〗To study the effect of probiotics on blood routine and plasma proteins in severe burns, and to explore the efficacy and value of probiotics in reducing burn inflammation.
  〖WTHZ〗Methods〖HTSS〗Eighty-eight burn patients were divided into intervention group(33 cases) and control group(55 cases) according to whether or not a probiotic preparation was used. The intervention group was given oral bifidobacterium live bacteria capsules for 14 days, and the conventional treatment of burns in the two groups was consistent. Blood routine and plasma proteins before and 14 days after application were recorded and statistically analyzed.
  〖WTHZ〗Results〖HTSS〗The white blood cell count, neutrophil percentage, and lymphocyte count of the two groups were lower than those before the treatment. Both were lower than before medication, and the monocyte count in the intervention group was higher than that before medication, and the differences were statistically significant(P<0.05). After treatment, the white blood cell count, neutrophil percentage, lymphocyte percentage, and platelet count of the intervention group were lower than those of the control group, and the monocyte counts were higher than those of the control group, and the differences were statistically significant(P<0.05). After administration, the albumin in the interference group was lower than before administration, and the total protein was higher than that before administration. The differences were statistically significant(P<0.05). After administration, albumin in the interference group was higher than that in the control group, and the difference was statistically significant(P<0.05).
  〖WTHZ〗Conclusion〖HTSS〗The clinical application of probiotics can reduce the inflammatory response and body damage after burns.

Key words: burn, systemic inflammatory response syndrome, probiotics