Journal of Hebei Medical University ›› 2022, Vol. 43 ›› Issue (10): 1163-1166,1196.doi: 10.3969/j.issn.1007-3205.2022.10.010

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Correlation analysis of visual function recovery with changes in blood flow of capillaries in the macula after idiopathic macular hole surgery

  

  1. 1.Department of Ophthalmology, Sanya People′s Hospital, Hainan Province, Sanya 572000, 
    China; 2.Department of Ophthalmology, the First Affiliated Hospital of Hainan Medical 
    University, Haikou 570100, China

  • Online:2022-10-25 Published:2022-11-16

Abstract: Objective To observe and analyze the changes in blood flow of capillaries in the macula and their correlation with the visual function recovery in IMH patients after surgery. 
Methods A total of 75 patients with monocular IMH were selected as the observation group, with the affected eye as group A, and the contralateral healthy eye as group B. Another 75 eyes of healthy physical examinees were selected as the control group. The area of foveal avascular zone(FAZ) and blood flow area and blood flow density of superficial retinal capillaries(RSCP), deep retinal capillaries(RDCP), and superficial choroidal capillaries(CSCP) in the center of FAZ before treatment were observed and compared in the three groups, The correlation between related indicators and best corrected visual acuity(BCVA) recovery in group A before treatment and at 3 months and 6 months after treatment was observed. 
Results Before operation, FAZ of group B and control group was lower than that of control group. RDCP blood flow density, CSCP blood flow area and blood flow density were higher than those of group A, the operations of the patients in group A were successfully completed. The patients were followed up for 6 months after the operation. The macular hole closure rate was 100%. The patient's BCVA was (1.14±0.27) LogMAR before surgery, (0.87±0.15) LogMAR at 3 months after operation, and (0.84±0.13) at 6 months after operation. The FAZ at 3 and 6 months after the operation was lower than before the operation, RDCP blood flow density, CSCP blood flow area, and blood flow density were higher than those before surgery, and the differences were statistically significant(P<0.05). The postoperative visual acuity recovery was negatively correlated with FAZ(P<0.05), and positively correlated with RDCP blood flow density, CSCP blood flow area and blood flow density(P<0.05).
Conclusion The occurrence of macular hole in IMH patients is closely related to FAZ and changes in macular blood flow. The area of FAZ and the blood flow density and blood flow area of RDCP and CSCP of the patients after the operation have been significantly improved. There is a significant negative correlation between the patient′s long-term vision recovery and postoperative FAZ area, and a positive correlation with blood flow density and blood flow area, which can be used as a good prognostic indicator for postoperative vision recovery in IMH patients.


Key words: idiopathic macular hole, best corrected visual acuity, capillary blood flow, correlation analysis