Abstract: Objective  To investigate the value of ultrasonographic evaluation of subendometrial resistance index (RI), pulsatility index (PI) and peak systolic blood flow velocity (PSV) values in predicting endometrial status and ovarian reserve function (ORF) in infertile patients. 
Methods  A total of 140 female infertile patients were included as the observation group (83 cases with normal ovarian function and 57 cases with abnormal ovarian function), and 100 healthy women who had given birth during the same period were selected as the control group. Transvaginal Doppler ultrasonography was performed in both groups to measure the values of subendometrial RI, PI and PSV and observe the endometrium simultaneously. Pearson correlation was used to analyze the correlation between RI, PI and PSV values and endometrial conditions, and the predictive efficacy of RI, PI and PSV values on ORF in infertile patients was analyzed by receiver operating characteristic (ROC) curve. 
Results  The PI and RI values of uterine artery in observation group were higher than those in control group, while the PSV values were lower than those in control group (P＜0.05). The endometrial volume and the number of B-type and C-type endometrium in the observation group were higher than those in the control group, while the endometrial thickness was lower than that in the control group (P＜0.05). Correlation analysis showed that PI and RI values were negatively correlated with endometrial thickness, but positively correlated with endometrial volume and endometrial type. PSV value was positively correlated with endometrial thickness and negatively correlated with endometrial volume and endometrial type (P＜0.05). The RI and PI values of uterine artery in the normal ovarian function group were lower than those in the abnormal ovarian function group, and the PSV values were higher than those in the abnormal ovarian function group (P＜0.05). ROC results showed that the area underthe ROC curve (AUC) of RI, PI and PSV values in predicting ovarian function in infertile patients were 0.648 (0.518-0.777), 0.715 (0.595-0.835) and 0.807 (0.736-0.922), respectively; the sensitivity were 62.51%, 62.48% and 81.21%, respectively, and the specificity was 75.04%, 65.08% and 72.52%, respectively. The AUC of combined diagnosis was 0.905 (0.878-0.984), the sensitivity was 84.43%, and the specificity was 87.56%. The diagnostic efficacy of combined detection for ORF in infertile patients was superior to that of single detection. 
Conclusion  〖JP2〗There are significant differences in the values of subendometrial RI, PI and PSV values between women with infertility and healthy women. The ultrasonographic evaluation of RI, PI and PSV values can effectively predict the endometrial status and ORF of infertile patients, and the combined detection of the three parameters has a higher predictive value. 

Key words: infertility, female, endometrium, ovarian reserve function, ultrasonography