The application of hepatectomy conbined with selective devascularization in primary hepatocellular carcinoma complicated with moderate/severe portal hypertension

doi:10.3969/j.issn.10073205.2016.08.011

Abstract

Abstract: [
Abstract ] Objective Toinvestigatetheclinicalefficacyofhepatectomyconbined with
selectivedevascularizitioninthetreatmentofprimaryhepaticcarcinoma ( PHC ) complicatedwith
moderate / severeportalhypertension.Methods Clinicaldata of53 patientsof PHC with
moderate / severeportalhypertensionfrom Nov. 2009toNov. 2014wereretrospectivelyananlyzed.
Patientsweredividedintotwogroupsaccordingtothesurgery methods : 23patientsreceived
hepatic-resectionin conbination with splenectomy and selective devascularizition ( observed
group ); 30 patientsreceived hepatic-resectioninconbination withsplenectomyand normal
devascularizition ( controledgroup ) .Clinicalresults werecomparedbetweenthetwogroups.
Results Thewhitebloodcell ( WBC ) andplatelet ( PLT ) wereimprovedafterthesurgeryinboth
groups ( P <0.05 ) andtheimprovementwasbetterintheobservedgroup (
P <0.05 ) .Alltheliver
functionstandardswereimproved ( P <0.05 ) afterthesurgeryinbothgroupsexcepttheALB ,
whiletheimprovementwasbetterintheobservedgroup ( P <0.05 ) .Theaccumulativeincidence
ofhemorrhageofdigestivetractwashigherinthecontroledgroup ( P <0.05 ) .Therewereno significantdifferencesbetweenthetwogroupsregardtothecomplications ( P >0.05 ) andalsothe
medicaleconomicsstandardssuchasthehospitalizationexpensesorlengthofstay ( P >0.05 ),
amongwhichthelengthofsurgeryintheobservedgroupwasexcluded ( P <0.05 ) .Conclusion
Hepatectomyconbinedwithselectivedevascularizationiseffectiveinthemanagementofprimary
hepaticcarcinomacomplicatedwithmoderate / severeportalhypertension.

Key words: liverneoplasms , hypertension, portal , treamentoutcome

FAN Rengen1， ZHOU Yong1, ZHA Wenzhang1, SHAN Xiangxiang2*. The application of hepatectomy conbined with selective devascularization in primary hepatocellular carcinoma complicated with moderate/severe portal hypertension[J]. Journal of Hebei Medical University, doi: 10.3969/j.issn.10073205.2016.08.011.

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The application of hepatectomy conbined with selective devascularization in primary hepatocellular carcinoma complicated with moderate/severe portal hypertension

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