Journal of Hebei Medical University

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Effect of dexmedetomidine on sedation on  the postoperative sleep status of  type 2 diabetes elderly patients undergoing spinal anesthesia

  

  1. 1.Department of Anesthesia, the People′s Hospitol of Jinzhou City, Hebei Province, Jinzhou 052260,
    China; 2.Department of Anesthesia, the First Hospitol of Shijiazhuang City, Hebei Province,
    Shijiazhuang 050011, China; 3.Department of Anesthesia, the People′s Hospitol Botou
    City, Hebei Province, Botou 062150, China; 4.Department of  Anesthesia, the
    Hospitol of Yuanshi County, Hebei Province, Yuanshi 051130, China
  • Online:2016-11-25 Published:2016-12-14

Abstract: [
Abstract ] Objective Toevaluatetheeffectofdexmedetomidineassistedsedationonthe
postoperativesleepstatusofelderlydiabetespatientsundergoingspinalanesthesia.Methods
Fortypatientsunderspinalanesthesiaonsaphenousveinligationandstrippingelectivesurgery
wererandomlydividedintotwogroups ( n =20 ): dexmedetomidinesedationgroup ( groupD ) and
controlgroup ( groupC ) .Thesleepqualityoflastmonthinallthepatientswereassessedusing
thePittsburghSleep QualityIndex ( PSQI ) thedaybeforeoperation.Whenlumbarepidural
anesthesiakeepstable , groupDbegancontinuousintravenousinfusionwithdexmedetomidine0.2
μ g ·
kg
-1 · h -1 ,
groupCwithsalineinfusion.Bothgroupswerebloodglucosemonitoredatthree
timepoints : immediatelyafterpuncture ( T 1 ), onehouraftertheoperationstart ( T 2 ), attheend ofoperation ( T 3 ) .OnemonthlaterthesleepqualityofallthepatientswereassessedusingPSQI
onceagain.Results Therewasnosignificantdifferenceincomparisonofbloodglucoselevels
betweenthetwogroups , betweentheT 1 -T 3 timepoints , andbetweentheinteractionofgroup · time
points ( P >0.05 ), andnodifferenceinthePSQIscores (
P >0.05 ), whilepostoperativePSQI
scoresinthetwogroupswerelowerthanthatbeforeoperation , andthedexmedetomidinegroup
waslowerthanthatofthecontrolgroup ( P <0.05 ) .Conclusion Dexmedetomidinegivenspinal
anesthesiaassistsedationcanimprovepostoperativesleepstatusoftheelderlypatientswithtype
2diabetetoacertainextent.

Key words: diabetesmellitus, type2 , anesthesia, spinal , dexmedetomidine , sleep