Abstract: ［Abstract］Objective〖HTSS〗〓To investigate the ovarian response, embryo quality and others outcomes of patients with ovarian endometriosis cyst and no surgery performed treatment before in vitro fertilizationembryo transfer(IVFET).
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓The clinical data in infertility women of ovarian endometriosis cyst with no surgery treatment performed in reproductive medicine center in the second hospital of Hebei medical university undergoing IVFET were performed by retrospective analysis. Fiftyeight cases of ovarian endometriosis cyst with no surgical treatment was used as endometriosis(EM) group, with the same period 55 cases of tubal factor in IVF was used as control group. GnRHa super long protocol was used for the ovarian stimulation. Clinical indexes(such as ovarian response to gonadotropin, number of oocytes), laboratory indexes(such as number of good quality embryos) and IVF pregnancy outcome were observed and compared between the EM group and the control group.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓There were no significant difference in the mean age, the duration of infertility, the base follicle stimulating hormone level, the duration of goadotropins, the goadotropins consumption, the number of transferred embryos between the EM group and control group(P＞005). The serum estradiol level on the human chorionic gonadotropin injection day, the number of retrieval oocytes in EM group, were lower than those in the control group, and the differences were statistically significant(P＜005). In the EM group the fertilization rate, the high quality embryo rate were lower than those in the control group, the difference was statistically significant(P＜005). The clinical pregnancy rate in the EM group was lower than that in the control group, but there was no statistically significant difference.
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓Endometriosis cyst may have certain negative effects of ovarian response and embryo quality in IVF. It may reduce the number of retrieval oocytes and good quality embryos, which could eventually affect pregnancy outcomes.

Key words: endometriosis； ovarian cysts, fertilization in vitro