Abstract: ［Abstract］ Objective〖HTSS〗〓To evaluate the technique and curative effect of minimally invasive transfrontal craniopuncture for spontaneous basal ganglia hemorrhage.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓The microanatomy and technique of minimally invasive transfrontal craniopuncture were elaborated. Sixtyfive patients with basal ganglia hemorrhage were urderwent CTguided  minimally invasive transfrontal craniopuncture. The hematoma was aspirated and the urinary plasminogen activator was injected into the hematoma through a soft catheter to promote the evacuation of hematoma. The evacuation rate of hematoma, the common complications, and the stroke scales were recorded, containing Glasgow Coma Scale(GCS), National Institutes of Health Stroke Scale(NIHSS), and Barthel Index(BI). The shortterm and longterm efficacy was evaluated.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓The GCS score at 1 week and 3 months after operation was significantly higher than that before the operation, and the postoperative GCS scores at 3 months were significantly higher than of 1 week. 1 week and 3 months after operation, the NIHSS score was lower than that before operation, and the 3 months after operation were lower than 1 week after operation, the difference was statistically significant(P＜0.05). The evacuation rate of hematoma was 88.1%. There were 24 patients（36.9%） in grade one of BI score, 23 patients（35.4%） in grade two, 9 patients（13.8%） in grade three， 5 patients（7.7%） in grade four，3 patients（4.6%） in grade five. There were 3 patients（4.6%） with rebleeding, 2 patients（3.1%） with intracranial infection, and 1（1.5%） death.
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓The minimally invasive transfrontal craniopuncture technique could remove the hematoma of small and medium volume basal ganglia effectively, improve neurological outcome, and significantly improve the activities of daily living. It is easy to operate, and is a safe and practical technique in treating cerebral hemorrhage.

Key words: cerebral hemorrhage； , minimally invasive craniopuncture； urokinasetype plasminogen activator