Abstract: ［Abstract］〓Objective〖HTSS〗〓To evaluate transcranial colorcoded sonography(TCCS) and magnetic resonance angiography(MRA) in screening of diagnosing unilateral middle cerebral artery(MCA) stenosis by using receiver operating characteristic(ROC) curve analysis. 
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓A total of 127 patients with unilateral middle cerebral artery(MCA) stenosis were enrolled in this study. TCCS, MRA and CT angiography(CTA) of head and neck were performed in all patients. Based on CTA results,137 normal MCA of root in the control group, 117 MCA with stenosis were divided into 4 categories: normal, mild stenosis, moderate stenosis and severe stenosis, then the data were evaluated using ROC curve analysis.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓The two diagnostic methods of TCCS and MRA were of high value in the diagnosis of stenosis in the unilateral MCA. The area under the curve of TCCS and MRA were 0.989(95%CI 0.967-0.998) and 0.991(95%CI 0.970-0.999), and the area under the curve was not statistically significant(P＞005).The diagnostic value of MRI was higher than that of TCCS in the diagnosis of mild to moderate stenosis in the unilateral MCA. The area under the curve was 0.959(95%CI 0.796-0.941) and 0.882(95%CI 0.894-0.989) respectively, and the area under the curve was statistically different(P＜005). In the diagnosis of moderate to severe stenosis, both methods have high value, and the area under the curve is 0.939(95%CI 0.847-0.984) and 0.955(95%CI 0.868-0.991) respectively, and the area under the curve is not statistically significant(P＞005). 
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓Both TCCS and MRA tests have high diagnostic value as a method for screening the arterial stenosis in the unilateral MCA, especially in the diagnosis of mild to moderate stenosis, the diagnostic value of MRA is higher than that of TCCS.

Key words: middle cerebral artery stenosis, ultrasonography, Doppler, color； magnetic resonance imaging