Abstract: ［Abstract］〓Objective〖HTSS〗〓To explore the effect of patient control epidural analgesia(PCEA) combined with intermittent epidural bolus(IEB) analgesia on T lymphocyte subsets and motor functions in pregnant women.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓The 140 cases of fullterm advanced maternal age were selected. According to the random number table method, they were divided into observation group(n=70) and control group(n=70). The control group was anesthetized with PCEA combined with continuous epidural infusion(CEI), the observation group was anesthetized with PCEA combined with IEB. Compared the analgesic effects, indexes of intraoperative and postoperative operation in parturient, motion block, T lymphocyte subsets and inflammatory factor levels before and after anesthesia in both groups.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓The Visual Analogue Scale(VAS) scores of both groups decreased first and then increased. The VAS score of the observation group was significantly lower than that of the control group, the difference of interblock, time points and interblock·time points was statistically significant（P＜005）. The number of PCEA addition, the dosage of ropivacaine, sufentanil and caesarean section cases in the observation group were less than those in the control group, and the maternal satisfaction in the observation group was higher than that of the control group（P＜005）. The incidence of motor block in the observation group was significantly lower than that in the control group(P＜005). There was no significant difference between the two groups on the first, second and thirdstage of labor time, analgesic time, interval and duration timeofuterine contraction, fetal heart rate, the number of patients using oxytocin，pregnant women adverse reactions, neonate Apgar scores 1 and 5 minutes after birth（P＞005）. The levels of CD3+, CD4+, CD4+/CD8+, interleukin 6(IL6) and tumor necrosis factor α(TNFα) had the trend of decrease in both groups. The CD3+, CD4+ and CD4+/CD8+ of the observation group were higher than those of the control group, and IL6 and TNFα were lower than those of the control group, the difference of interblock, time points and interblock·time points was statistically significant（P＜005）. The difference of interblock, time points and interblock·time points on CD8+ in the two groups was not statistically significant（P＞005）.
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓The analgesic effect of PCEA combined with IEB on aged parturient was significant, the dosage of anesthetic was less, the patient satisfaction was high, it can reduce the rate of cesarean section and the occurrence of motor block, and improve the immune suppression and inflammation, which is worth popularizing.

Key words: parturition； analgesia； Tlymphocyte subsets, motor function