Abstract: Objective To evaluate the clinical application value of 64-slice CT angiography (64-SCTA),magnetic resonance angiography( MRA ) for the skull basal vertebral artery stenosis compared with digital subtraction angiography(DSA);To explore the value of 64-SCTA,MRA and DSA in detecting the nature of plague of the skull basal segment of vertebral artery. Methods A total of 50 patients diagnosed posterior circulation ischemia underwent 64-SCTA,MRA and DSA in our hospital. Their images were retrospectively analyzed. The constituent ratio of 64-SCTA,MRA and DSA for the skull basal vertebral artery stenosis were calculated. The results of 64-SCTA,MRA and DSA were analyzed statistically. The accuracy,sensitivity and specificity were respectively calculated for 64-SCTA and MRA by the“gold standard”for DSA. The results of 64-SCTA and MRA were analyzed statistically. The density of plague of the skull basal segment of vertebral artery was detected. The results of 64-SCTA,MRA and DSA were analyzed respectively. Results There were significant difference among 64-SCTA,MRA and DSA in diagnosing the constituent ratio of the skull basal vertebral artery stenosis. 64-SCTA,MRA had higher accuracy,sensitivity and specificity in diagnosing the V4 - 5 segment of vertebral artery stenosis. MRA had the lowest accuracy,sensitivity and specificity in diagnosing the V2 - 3 segment of vertebral artery stenosis,and the comparison between 64-SCTA,MRA and DSA in diagnosing plague nature of the skull basal vertebral artery showed significant difference. Conclusion 64-SCTA,MRA in evaluating the V4 - 5 segment of vertebral artery stenosis proved higher diagnostic value;64-SCTA in detecting plague nature of the skull basal vertebral artery has higher accuracy than DSA,especially in MRA,64-SCTA has significance in guiding clinical treatment.

Key words: vertebrobasilar insufficiency, diagnostic imaging, comparative study