Abstract: ［Abstract］ Objective〖HTSS〗〓To investigate the expression and changes of T lymphocyte subsets and blood routine parameters of gastric cancer patients.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓A total of 224 subjects were recruited and divided into two groups:98 controls and 126 gastric cancers, T lymphocyte subsets were measured by flow cytometry and blood routine test was measured by automatic analyzer.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓CD3+T and CD4+T lymphocytes were decreased significantly(P＜005), the ratio of CD4+/CD8+ was decreased slightly(P＞005) and CD8+T cells seemed did not change, the white blood cell count, neutrophil and neutrophil/lymphocyte ration of the case group were higher than the control group and lymphocyte, hemoglohin were lower(P＜005).
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓The balance of T lymphocyte subsets in patients with advanced gastric cancer was abnormal, while CD3+ and CD4+T lymphocytes were significantly decreased. Peripheral blood neutrophils increased, lymphocytes decreased, and neutrophil to lymphocyte ration increased. Determination of T lymphocyte subsets and neutrophil/lymphocyte ration in patients has certain clinical value for treatment and prognosis.

Key words: gastric cancer , Tlymphocytes, leukocytes