Abstract: ［Abstract］〓Objective〖HTSS〗〓To study the clinical effect of endoscopic combined lowincision operation in patients with benign thyroid nodules.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓One hundred and twenty patients with benign thyroid nodules were selected and randomly divided into two groups(60 cases each). The control group was treated with open thyroid surgery. The observation group was treated with endoscopic combined low incision operation. The operation condition, immune function index, postoperative complications, postoperative pain score, serum inflammatory factor index were compared between the two groups.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓The incision length of the observation group was shorter than that of the control group, and the intraoperative blood loss was less than that of the control group(P＜005). However, there was no statistical difference in operation time between the two groups(P＞005). After surgery, the CD3+ and CD4+/CD8+ in the two groups were lower than those before surgery, while the CD3+ and CD4+/CD8+ of the observation group were higher than those of the control group(P＜005). The total incidence of postoperative complications was lower in the observation group than in the control group(P＜005). Postoperative pain scores showed a decreasing trend at each time point, and the observation group was lower than the control group. There were significant differences in the interaction between the groups, between the time points, and between groups and time points(P＜005).The levels of Creactive protein, interleukin6 and procalcitonin in the observation group were lower than those in the control group(P＜005).
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓In the treatment of benign thyroid nodule, the length of incision is shortened by endoscopy combined with low incision, which can effectively reduce the amount of intraoperative bleeding, reduce postoperative complications, protect the immune function of patients and inhibit inflammatory factors.

Key words: thyroid nodule, endoscopes, low incision, inflammatory factors, immune index