Abstract: Objective  To investigate the clinical outcomes of minimally invasive extraction of supernumerary teeth in premolar region under Cone beam Computer Tomography(CBCT) guidance, and provide reference concerned. 
Methods  Patients with supernumerary teeth in premolar region and accepted the tooth extraction by oral implant machine under the guidance of CBCT were collected. The distribution of supernumerary teeth in upper and lower jaw, position characteristics, operation duration and postoperative reaction were analyzed. 
Results  The ratio of supernumerary teeth located in the mandible of premolar region was 70.13%. Supernumerary teeth impacted on the lingual(palatal) side has accounted for 89.61%. The average operation time of supernumerary teeth in maxilla was(26.96±7.60) min, and in mandible was(27.70±7.35) min. Visual Analogue Scale（VAS） score was respectively(maxilla 2.48±0.90， mandible 2.54±0.98） one day after extraction and(maxilla 0.57±0.51， mandible 0.59±0.53) seven days after extraction. 
Conclusion  Supernumerary teeth in premolar region are always impacted in the lingual side(89.61%). Combined application of CBCT and implantology surgical unit can not only reduce the operation time of extracting supernumerary teeth located in premolar region, but also reduce the trauma and postoperative complications.

Key words: tooth extraction, bicuspid, spiral cone-beam computed tomography