Journal of Hebei Medical University

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Correlation of procalcitonin level with the severity and prognosis of hip joint tuberculosis

  

  1. 1.Department of Spine Surgery, the Third Hospital of Hebei Medical University, Shijiazhuang
    050051, China;2.Department of Bone Disease, the Third Hospital of
    Hebei Medical University, Shijiazhuang 050051, China
  • Online:2020-04-25 Published:2020-05-15

Abstract: [Abstract] Objective〖HTSS〗To investigate the correlation of procalcitonin(PCT) level with the severity of hip joint tuberculosis and its value in predicting the prognosis.
 〖WTHZ〗Methods〖HTSS〗The clinical data of 166 patients with tuberculosis of hip joint were analyzed retrospectively. According to babhulkar's criteria, the patients were divided into four groups: group A(stage Ⅰ, synovitis stage), 58 cases; group B(stage Ⅱ, early arthritis stage), 51 cases; group C (stage Ⅲ, arthritis stage), 33 cases; group D (stage Ⅳ, late arthritis stage), 24 cases. Patients in groups A and B were treated with oral anti-tuberculosis drugs, and patients in groups C and D were treated with surgery and anti-tuberculosis drugs. The changes of PCT in each group at different time points was observed and compared. The visual analog scale(VAS) was used to evaluate the pain and the Harris score was used to evaluate hip function.
 〖WTHZ〗Results〖HTSS〗With the gradual aggravation of the lesion, the PCT concentration and VAS score gradually increased, and the Harris score gradually decreased, and the difference between the groups was statistically significant(P<0.05). From 2 weeks of anti-tuberculosis drug treatment to 1 year after surgical treatment, the PCT concentration, VAS score and Harris score of the 4 groups of patients changed significantly, the difference was statistically significant.
 〖WTHZ〗Conclusion〖HTSS〗In patients with tuberculosis of hip joint, the severity of joint disease is positively related to the level of PCT. Antituberculous drugs can reduce the level of PCT, but after surgery, PCT decreases faster, hip pain relief is better, and hip function recovery is better.

Key words: tuberculosis, osteoarticular, hip joint; procalcitonin