Journal of Hebei Medical University

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The method and evaluation of hematuria detection in two kinds of urine dry chemistry analyzer

  

  1. Department of Laboratory Medicine, the Second Hospital of Hebei Medical University, Shijiazhuang 050000, China
  • Online:2020-08-25 Published:2020-08-26

Abstract: Objective  To clarify the rules of two urine dry chemical analyzers in detecting hematuria with different hemoglobin concentrations, and to explore the relevant measures.
Methods  Fifteen simulated hemoglobin samples with different hemoglobin concentrations were prepared. The parallel control tests were carried out in centrifugation or not with Kebao XL automatic urine analyzer and Beckman IRIS iQ200 automatic urine analyzer. 11 detection Results   were compared and analyzed.
Results  When the hemoglobin concentration in the sample arrive 1 g/L, the COMBI XL automatic urine analyzer will report the false positive Results   of WBC. With the hemoglobin concentration increasing,bilirubin, nitrite, ketone body, urinary cholanogen, SG and vitamin C would be reported false positive Results   in turn. When the hemoglobin concentration was 5 g/L, the Beckmann IRIS iQ200 automatic urine analyzer would report the false positive Results   of BIL, and when it reached 19 g/L, KET false positive Results   would appear. Other effects hadn't been found in these detections.
Conclusion  When the hematuria samples in different hemoglobin concentrations were detected with the two urine dry chemical analyzers, their respective anti-interference characteristics should be taken consider.

Key words: hematuria, hemoglobin, dry chemical analyzer