Journal of Hebei Medical University ›› 2021, Vol. 42 ›› Issue (2): 222-227.doi: 10.3969/j.issn.1007-3205.2021.02.022

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Application of virtual reality situational interactive training in the rehabilitation treatment of patients with Alzheimer′s disease in nursing home

  

  1. 1.Department of Muchunyuan Nursing Home， Geriatric Hospital of Nanjing Medical University， Jiangsu 
    Province, Nanjing 210024， China； 2.Rehabilitation Medical Center, the First Affiliated Hospital of 
    Nanjing Medical University， Jiangsu Province, Nanjing 210029，China；3.Department of 
    Rehabilitation Center， Nanjing Jiangning Muchunyuan Nursing Home, Jiangsu Province
    Nanjing, 211100, China; 4.Department of Dementia Rehabilitation Center, Nanjing 
    Jiangning Muchunyuan Nursing Home， Jiangsu Province, Nanjing 211100，China
  • Online:2021-02-25 Published:2021-03-09

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Abstract: Objective  To investigate the effect of rehabilitation therapy of virtual reality（VR） situational interactive training on patients with Alzheimer′s disease（AD） in nursing home. 
Methods  A total of 56 patients with AD in nursing home were randomly divided into control group(n=28) and observation group(n=28). The control group was treated with routine care service of the nursing home and health education. The observation group was given 6 months of VR situational interactive training on the basis of the control group， 45 min each time and 3 times per week. All patients were assessed with cognitive function［mini-mental state examination（MMSE） and AD assessment scale-cognition（ADAS-cog）］， motor function［timed up and go test（TUGT）， 30-second chair stand test（30 sCST）， 30-second arm curl test（30 sACT） and chair sit-and-reach test（CSRT）］， activity of daily living(ADL)［ADL scale］ and quality of life［quality of life-Alzheimer's disease(QOL-AD)］ before and after intervention. 
Results  After intervention， the MMSE scores and the ADAS-cog scores of the observation group were significantly improved, as compared with those before intervention and better than those of the control group(all P＜0.05). The test results of the TUGT， 30 sCST， 30 sACT and CSRT of the observation group were significantly improved, as compared with those before intervention and better than those of the control group（all P＜0.05）. The ADL scores and the QOL-AD scores of the observation group were significantly improved, as compared with those before intervention and better than those of the control group（all P＜0.05）. However, there were no significant differences in the above evaluate test indicators in the control group, as compared with those before intervention（P＞0.05）. 
Conclusion  VR situational interactive training could effectively improve the cognitive function, motor function and ADL， and could increase the quality of life of AD patients in nursing home. Therefore, it is worthy of promotion and application in nursing home. 


Key words: Alzheimer′s disease, virtual reality situational interactive training, nursing home