Abstract: Objective To explore the clinical characteristics and curative effect of neonatal aspiration pneumonia.Methods Seventy-eight cases with neonatal aspiration pneumonia were randomly divided into three groups,each group 26 patients,C group with conventional treatment of neonatal aspiration pneumonia,A group with ambroxol hydrochloride on the basis of C group, and B group with budesonide and ambroxol hydrochloride treatment on the basis of C group.The total efficiency,the clinical symptoms and signs disappeared time,hospital stay,the incidence of adverse reactions of three groups were compared after seven days of treatment.Results The total efficiency in A group(92.31%)and B group(96.15%)were higher than that in C group(76.92%). The difference were statistically significant among three groups(P < 0.05).Breathing difficulty disappeared time,Cyanosis disappeared time and lung rale disappeared time of A group and B group ware earlier than those of C group.And the effect of B group was better than C group. Conclusion Ambroxol(A group)or budesonide jointed ambroxol(B group)in the treatment of neonatal aspiration pneumonia has achieved better clinical results,and improved the clinical signs and symptoms,the medication is safe and reliable,which will help the quick recovery of the children.

Key words: pneumonia, aspiration, treatment outcome, infant, newborn