The impact and possible mechanisms of operation time on the postoperative recovery of elder patients with laparotomy#br#

doi:10.3969/j.issn.10073205.2016.09.016

Abstract

Abstract: [
Abstract ] Objective Toinvestigatetherelationshipbetweenpostoperativerecoveryand
operationtimeinelderlypatientsundergoingopensurgery.Methods Clinicaldataof80gerontal
patientswithlaparotomyundergeneralanesthesiaatourhospitalwasretrospectivelyanalyzed.
Patientsweredividedintotwogroupsaccordingtotheoperationtime , groupA ( operationtime<
3hours ) andgroupB ( operationtime≥3hours ) .Theclinicaldata ( includinggeneralinformation
andthesurgery-relatedinformation ), thepostoperativerecoveryrelatedindexesandthelevelsof
inflammatoryfactorsbeforeandaftertheoperationofpatientsintwogroupswerecompared.
Results Thetransfusion quantity , dosageofpropofol , operationtime , recoverytime of
spontaneousbreathing , extubationtime , recoverytimeandtheadversereactionrateofdelirium ,
fluctuationofbloodpressureafteroperationofpatientsingroupAwereallobviouslylowerthan
thosein group B ( P <0.05 ) .There wasnostatisticaldifference withthebloodlossand
temperatureaftertheoperationintwogroups ( P >0.05 ) .Therewerenosignificantdifferencesin
thelevelsofC-reactiveprotein ( CRP ), tumornecrosisfactor-α ( TNF-α ), interleukin-2 ( IL-2 ) and interleukin-6 ( IL-6 ) betweenthe2groupsbeforetheoperation.At12hafteroperation , thelevels
ofCRP , TNF-α , IL-2andIL-6wereallsignificantlyincreasedintwogroups.Furthermore , the
levelsofCRP , TNF-α , IL-2andIL-6ingroupAwereallsignificantlylowerthanthoseingroup
B ( P <0.05 ) .Conclusion Theoperationtimehadimportantinfluenceonpostoperativerecovery
ofgerontalpatients.Theinvolved mechanismswerecorrelated withthedosageof

Key words: surgicalprocedures, operative , timefactors , recovery , aged

HANG Taixiang, WU Shanshan, WANG Yujie, ZHANG Yu*. The impact and possible mechanisms of operation time on the postoperative recovery of elder patients with laparotomy#br#[J]. Journal of Hebei Medical University, doi: 10.3969/j.issn.10073205.2016.09.016.

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The impact and possible mechanisms of operation time on the postoperative recovery of elder patients with laparotomy#br#

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