Abstract: [
Abstract ] Objective Toassessthevarietyandsignificanceofserumcalcium , magnesium ,
phosphorus , parathyroidhormone ( PTH ), andrelatedclinicalriskfactorsofparathyroidinjury
aftertotalthyroidectomy.Methods One hundred and twenty-nine patients with total
thyroidectomy , consistingof82caseswiththyroidpapillarycarcinomaand47caseswithNodular
goiterandthyroidadenoma , wereretrospectivelystudied.Levelsofserumcalcium , magnesium ,
inorganicphosphorusandPTHbeforeoperationand30minutes , 1d , 3dafteroperationwere
measuredrespectively , andage , gender , preoperativethyroidstimulating hormone (
TSH ),
intraoperativeidentificationofparathyroidglands , pathologicdiagnosiswerecounted.Andthen
therelationshipbetweentheabovefactorsandhypocalcemiawhichaffectedbyparathyroidinjury
afteroperationwereanalyzedrespectively.Results Serumcalcium , magnesiumandPTHlevels
afteroperationintotalthyroidectomypatients werealllowerthanthosebeforeoperation ,
especiallyserumcalciumandmagnesiumlevelsin1dayafteroperationdecreasedsignificantly ,
andserumPTHlevelsdeclinedin30minutesafteroperation.Therewerestatisticallysignificant differencesonserumcalciumlevelsindifferentthyroidectomygroupsordifferenttimepoints
(
P <0.05 ), buttherewasnosignificantinteractionbetweenthetwogroupsatthesametime
P >0.05 ) .Andtherewerealsostatisticallysignificantdifferencesonserum magnesiumandPTH
indifferentgroups , differenttimepointsandtheinteractionbetweenthetwogroups ( P <0.05 ),
whiletherewasnosignificantdifferenceintheinteractionofserum phosphorusindifferent
groupsofallthegroups , betweendifferentpoints , andbetweenthetwogroups ( P >0.05 ) .
Among129caseswithtotalthyroidectomy , 77cases ( 59.7% ) werenormalserumcalcium , 31
cases ( 24.0% ) wereasymptomatichypocalcemia , and21casesweresymptomatichypocalcemia.
Theriskofhypocalcemiathyroidcancerunderwenttotalthyroidectomygroupaftersurgerywas
significantlyhigherthanthatinbenignthyroiddiseasegroup ( P <0.05 ) .Theidentification
numberandtheage , gender , parathyroidsurgerypreoperative TSH levelandpostoperative
hypocalcemiawerenotstatisticallysignificant ( P >0.05 ) .Conclusion Thescopeofoperationand
thyroidcancermaybetheinfluencingfactorsofparathyroidinjuryafteroperation.Afterthyroid
surgery , bloodPTH monitoringismoresensitivethanserumcalcium monitoring.Lowserum
calciumafterthyroidsurgeryisoftenaccompanywithlowserum magnesium , soserumcalcium
supplementneedsserum magnesiumsupplementatthesametime.

Key words: totalthyroidectomy , parathyroidinjury , hypocalcemia