Abstract: [
Abstract ] Objective Toexplorethecorrelationbetweenradiotherapysensitizationof β -
elemeneandtumorangiogenesis.Methods Whentransplantedtumorshadaccumulatedfor0. 8-
1. 0cm
3 ,
tumor-burdenednudemiceweredividedinto8groupsrandomly ( eachgroupforfive ),
whichincludes : blankgroup , 25mg / kgdrugsgroup , 45mg / kgdrugsgroup , 100mg / kgdrugs
group , theradiotherapygroup ( NaCl+radiotherapy ), 25mg
/ kgdrugs+radiotherapygroup , 45
mg
/ kgdrugs+radiotherapygroup , 100mg / kgdrug+radiotherapygroup.
β
-elemenewasinjected
accordingtodose , and NaClwasinjectedtoblankgroup.Volumedoublingtime ( VDT ) and
enhancementfactor werecompared between groups.Theexpression ofvascularendothelial
growthfactor ( VEGF ) andCD34werecomparedbetweengroups.Results VDTofB1 , C1and
D1groupwerehigherthantheA1 , andVDTofD1groupwashigherthanB1 , C1group , which
thedifferenceswerestatisticalsignificance ( P <0.05 ) .VDTofB2 , C2andD2groupwerehigher
thanA2group , andD2andC2groupwerehigherthanB2 ,
atthesametimeD2groupwashigher
thanC2group , whichthedifferenceshadstatisticalsignificance
( P <0.05 ) .Thedifference
betweenradiotherapygroupandno-radiotherapygroupwasnostatisticallysignificant ( P <0.05 ) .
Thedoseof45 mg
/ kgand100 mg / kghadsensitizationeffect.Averageopticaldensityand

Key words: lungneoplasms , chemoradiotherapy ;
β
-elemene