Abstract: ［Abstract］  Objective〖HTSS〗〓To explore the correlation between frailty index and postoperative complications of aged patients with nodular goiter, in order to provide reference evidence for clinical care.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓One hundred and twenty cases aged patients with ndular goiter undergoing operative treatment were selected as the research object. All of them were divided into three groups according to the frailty index as follows：nonfrail group(FI<0.08, 35 cases), intermediately frail group(FI≥0.08-0.25, 35 cases) and frail group(FI＞0.25, 50 cases). Collect clinical data of patients about general data, BMI, ASA classification, hospital stays and postoperative complications were examined. The correlation between the indexes above and frailty index was analysed.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓There was no significant difference between the 3 groups in the ASA classification（P＞0.05）. Frailty index and the ASA classification has some relevance, but less relevant according to the Spearman correlation analysis（ rs=0.265, P=0.007 ）. There was significant difference among the 3 groups in the incidence of complications and hospitalization time (P＜005). The incidence of complications in the frail group was higher than that in the nonfrail group(P＜005). The hospitalization time of intermediately frail group and frail group was longer than that of non weak group. The hospitalization time of the frail group was longer than that of the intermediately frail group（P＜005）. Spearman correlation analysis showed that FI was positively correlated with perioperative complications(rs=0.519, P=0.023). FI predicts that the ROC curve area of perioperative complications of surgical resection of nodular goiter is 0.812(CI:0.699-0.882, P=0.000）.
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓The level of frailty index is risk factor of postoperative complications of aged  patients with nodular goiter. The preoperative frailty index evaluation can provide reference evidence for the treatment of aged NG patients undergoing surgery with low postoperative complications rate.

Key words: goiter, nodular, postoperative complications, malnutrition