Abstract: ［Abstract］ Objective〖HTSS〗〓To investigate the relationship between the mutations in hepatitis B virus X gene and the postoperative survival in hepatocellular carcinoma.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓The HBV X gene was amplified and sequenced, and the HBV mutations were identified. The relationship between virological factors and HBVHCC survival was analyzed with the KaplanMeier method, the Logrank test and the Cox proportional hazards model.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓The following seven sites were associated with postoperative survival at statistically significant levels in HCC tissue: 1329， 1341， 1383， 1461， 1485， 1544， 1613. The following four mutational sites were identified for their association with survival at a borderline significance level: 1317， 1674， 1753， 1762/1764. The tumor size， portal vein thrombosis and the following five mutational sites were associated with postoperative survival in HCC patients: 1329， 1341， 1383， 1461, 1485. 
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓The tumor size，portal vein thrombosis and the following five mutational sites were identified as independent predictors of postoperative survival in HCC patients: 1329， 1341， 1383， 1461， 1485.

Key words: liver neoplasms； hepatitis B virus； , prognosis