Abstract: ［Abstract］〓Objective〖HTSS〗〓To study the effect of the removal of the corneal flap on the visual quality of high myopia with laserassisted subepithelial keratomileusis(LASEK) in the treatment of high myopia.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓The 60 eyes of 30 cases of high myopia given LASEK operation were divided into two groups. In all of these cases, one eye had offflap LASEK operation randomly，and the other eye was applied onflap LASEK operation as onflap group. All cases were followed up for 1, 3, 5, 7 days and 1, 3, 6 months. To compare visual acuity, spherical equivalent, postoperation pains, corneal epithelium healing, questionnaire survey of visual quality were observed.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓At 3 months postoperatively, the number of eyes of increments 1 line of best corrected visual acuity were significantly higher in the offflap group than those in the onflap group（P＜005）. At 3 and 6 months postoperatively, the spherical equivalent in bost groups showed a decreasing trend of positive sphere with the change of time, and the difference between the two groups was statistically significant(P＜005). The scores of postoperative pain stimulation symptoms in bost groups showed a decreasing trend with the change of time, and were lower in offflap group than those in onflap group, and there were significant differences between the two groups(P＜005). Compared to the onflap group, outcomes for the offflap group showed a higher percentage of corneal epithelial healing at 3 and 5 days after surgery(P＜0.05). At 1, 3 and 6 months postoperatively, the changes of visual acuity fluctuation, halo and ghost symptoms in both groups showed a decreasing trend with the change of time(P＜005). The difference between the two groups was statistically significant in ghost and overall satisfaction scores(P＜005). At all the three time points, the ghost scores were lower in offflap group than those in onflap group, and the overall satisfaction scores were higher in offflap group than those in onflap group.
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓Results of offflap LASEK for correcting high myopia showed the slighter stimulus pain and the shorter corneal epithelial healing time. The subjective visual quality was better and the overall satisfaction was higher in the early stage of offflap LASEK.

Key words: myopia, keratectomy, subepithelial, laserassisted, vision, ocular