Abstract: ［Abstract］ Objective〖HTSS〗〓To observe the clinical efficacy of vacuum sealing drainage(VSD) combined with stamp skin grafting in the treatment of soft tissue infections with defects.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓Twentyfour patients were selected with skin infections and defects admitted to Luoyang orthopedic hospital of Henan province. After vital signs became stable, all patients were received debridement surgery in the first stage, and VSD was used to continuously press and suck the wound for 5 to 14 days(replace one or two times) until the wound granulation tissue was fresh without infection. In the second stage, the intermediate split thickness skin graft was taken from inner thigh and was cut into stampshaped pieces of skin about 0.5 cm×0.5 cm. The wound was attached with skin pieces at a distance of 2 mm, then was covered by the meshy vaseline gauze. And the sterile dressing was used for pressurized bandage. After 7 days, the dressing was observed.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓Granulation tissues of all patients were granular, bright red, and free from infection after the first stage of treatment. Two weeks after stage Ⅱ skin grafting: 23 cases were excellent, 1 case was good, and there was no pain in the affected area. One patient failed to cover the wound completely because of sliding and overlapping of some skin flaps due to inappropriate movement, and the wound healed after repeated dressing changes in the later period. One patient had a small quantity of skin pieces that were dry and had poor activity(not necrotic) on the edge of the wound. They was coated with a thin layer of MEBO moist burn cream and survived on its own. After 3 to 12 months of followup, the color, elasticity, sensation and joint activity of the skin graft area were normal without secondary skin infection, necrosis, limb weight disability and secondary surgery.
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓VSD combined with stamp skin grafting in the treatment of skin and soft tissue infections of extremities and trunk with defects has the advantages of simple operation, short hospitalization time, low cost, definite curative effect and fewer complications, which is worthy of clinical promotion.

Key words: infection, skin transplantation, negative pressure wound therapy