Abstract: ［Abstract］ Objective〖HTSS〗〓To investigate the risk factors of systemic inflammatory response syndrome(SIRS) in elderly patients with upper urinary calculi treated by percutaneous nephrolithotomy.
〖HTH〗〖WTHZ〗Methods〖HTSS〗〓A retrospective analysis of 95 elderly patients with upper urinary calculi after percutaneous nephrolithotomy was performed to evaluate the correlation between the various factors and the postoperative SIRS.
〖HTH〗〖WTHZ〗Results〖HTSS〗〓Of the 95 patients, 22(23.2%) had SIRS, of which 2 had septic shock. After active antiinfection and supportive treatment, the patients recovered without death. History of diabetes mellitus, repeated urinary tract infection, positive rate of preoperative urine culture, the rate of staghorn calculi, stone load and operation time in SIRS group were significantly higher than those in nonSIRS group, and the difference was statistically significant. Logistic regression analysis showed that history of recurrent urinary tract infection, staghorn calculi, and diabetes mellitus were risk factors for SIRS in elderly patients after percutaneous nephroscopy.
〖HTH〗〖WTHZ〗Conclusion〖HTSS〗〓For elderly patients with history of recurrent urinary tract infection, staghorn calculi and diabetes mellitus, vigilance should be raised, infection should be actively controlled before operation, renal collecting system damage should be avoided during operation, and strict monitoring after operation should be done to reduce the incidence of SIRS.

Key words: systemic inflammatory response syndrome, urinary calculi, percutaneous nephrolithotomy