Abstract: Objective To explore the effect of early application of double-layer artificial dermis in the treatment of deep burn wounds of joints. 
Methods A total of 40 patients with severe and deep burn wounds of joints were selected as research subjects, and randomly divided into the observation group(n=20) and the control group(n=20) according to different treatment methods. In the observation group, the deep burn wounds of joints were treated with escharectomy or tangential excision at 3-5 d after injury, and then the wound were covered with Lando double-layer artificial dermis. After good vascularization of the artificial dermis, the silica gel layer was removed and the autologous split-thickness skin was grafted. In the control group, escharectomy or tangential excision was performed on deep burn wounds of joints at 3-5 d after injury, and then the thin split-thickness autograft was performed. The survival rate of skin graft at 7 d after implantation and the healing rate of wound surface at 21 d after implantation were recorded. After wound healing, the rehabilitation training was guided, the data on the incidence of joint blister, pain and pruritus were collected, and the quality of life of patients who suffered joint scar hyperplasia and burn was evaluated.  
Results The survival rate of skin grafts in the observation group was higher than that in the control group at dressing change at 7 d after skin graft surgery. The wound healing rate in the observation group was higher than that in the control group at 21 d after surgery. The incidence of blisters, pain, and pruritus in the observation group was lower than that in the control group, with statistical significance(P＜0.05). After 12 months of follow-up, according to the Vancouver Scar Scale score, the observation group had better scar hyperplasia than the control group. According to the BSHS-B score, the observation group had better quality of life after burn than the control group, with statistical significance(P＜0.05). 
Conclusion Double-layer artificial dermis can be safely applied to the early treatment of deep burn wounds of joints in patients, which has a high survival rate of skin grafts, low incidence of adverse wound events, insignificant scar hyperplasia at joints, and high quality of life for burn patients. 

Key words: burns, double-layer artificial dermis, joint wounds