Abstract: Objective The dosimetric parameters of bone marrow sparing-intensity modulated radiation therapy(BMS-IMRT) and conventional intensity modulated radiation therapy(IMRT) in patients with cervical cancer after hysterectomy were compared and analyzed, providing a theoretical basis for the clinical application of BMS-IMRT. 
Methods Ten patients with cervical cancer undergoing hysterectomy were selected to design BMS-IMRT and IMRT plans respectively, and the dosimetric indexes of the planning target volume(PTV) and organs at risk(OARs) were statistically analyzed. 
Results The mean value of Dmax and Dmean in BMS-IMRT group were higher than those in IMRT group and the homogeneity index(HI) of PTV in the BMS-IMRT group was inferior to that in IMRT group(P＜0.05). The mean V10, V20, V30, V40 of bone marrow in BMS-IMRT group were lower than those in IMRT group, and the Dmax of femoral heads was also lower in the BMS-IMRT group than in IMRT group(P＜0.05). The radiation dose of rectum and bladder in the two plans was not statistically significant(P＞0.05). 
Conclusion BMS-IMRT can reduce the radiation dose of bone marrow while ensuring the coverage of PTV compared with the conventional IMRT in postoperative patients with cervical cancer and dose not increase the radiation dose of the rectum and bladder, theoretically reducing the occurrence of hematological toxicity.

Key words: Cervical cancer, bone marrow sparing, radiation therapy, dosimetry