Abstract: Objective To explore the clinical application value of segmental wall motion abnormalities and myocardial fraction flow reserve(FFR) in the diagnosis of myocardial ischemia in coronary heart disease(CHD). 
Methods The clinical data of 95 patients with suspected myocardial ischemia in CHD were retrospectively selected for study. A total of 52 patients were diagnosed with myocardial ischemia in CHD by coronary angiography; all received echocardiography and FFR was detected. The positive predictive value, negative predictive value, accuracy, specificity, and sensitivity of the two indicators were further analyzed and compared, and the receiver operating characteristic(ROC) curve was analyzed. 
Results The positive predictive value of 95 patients with suspected myocardial ischemia in CHD after echocardiography was 81.63%, and the negative predictive value was 73.91%, which was lower than the gold standard(P＜0.05). The positive predictive value was 96.15% after FFR detection, and the negative predictive value was 95.35%, which was not significantly different, as compared with the gold standard(P＞0.05). The sensitivity, specificity, and accuracy of FFR were higher than those of echocardiography(P＜0.05). A total of 15 cases(71.43%) of anterior descending artery disease, 12 cases(75.00%) of circumflex artery disease, and 13 cases(86.67%) of right coronary disease were detected by echocardiography. FFR detected a total of 20 cases of anterior descending artery disease(95.24%), 15 cases of circumflex artery disease(93.75%), and 15 cases of right coronary disease(100.00%). The total detection rate of the two methods showed a significant difference(P＜0.05). The area under the ROC curve(AUC) of segmental wall motion abnormalities by echocardiography was 0.780(P＜0.05), and the AUC of FFR was 0.958(P＜0.05). 
Conclusion Compared with FFR, segmental wall motion abnormalities by echocardiography have higher predictive value and can provide objective evidence for the diagnosis of myocardial ischemia in CHD.

Key words: cardiac wall motion by echocardiography, myocardial fraction flow reserve, coronary heart disease, myocardial ischemia