关键词: 结核, 肺, 降钙素, 感染

Abstract: ［Abstract］ ObjectiveTo investigate the diagnostic value of CD64 on pulmonary tuberculosis with bacterial infection. MethodsA total of 200 patients, hospitalizing at the departments of respiration and tuberculosis in Hebei Chest Hospital were divided into two groups:Group Ⅰ(n=100), patients with pulmonary tuberculosis; Group Ⅱ(n=100), patients suffering pulmonary tuberculosis with bacterial infection. Firstly, we detected the level of CD64, procalcitonin(PCT), and Creactive protein(CRP) invenous blood drawn within 48 h after patients were enrolled in group. Secondly, ROC curves could be plotted based on the data of CD64，PCT and CRP. Finally, it was essential to account the area under curve, the best borderline of CD64, PCT and CRP. Then the sensitivity and specificity were caculated. ResultsCompared with Group Ⅰ，CD64 index，PCT and CRP in Group Ⅱ were increased significantly(P＜005). The area under curves plotted basing on the data from two groups were 0.971（CD64）>0921（PCT）>0.825（CRP）, respectively. Compared with the standard area of 0.5, there were statistical significance（P＜005）. ConclusionCD64 is highly expressed in infectious patients with pulmonary tuberculosis, whose diagnostic value is similar to PCT, whereas better than CRP. These results indicate that CD64 might be an assistant marker in diagnosing pulmonary tuberculosis with bacterial infection.

Key words: tuberculosis, pulmonary, calcitonin, infection