河北医科大学学报

• 论著 • 上一篇    下一篇

3种方法在诊断结核性胸膜炎中的价值

  

  1. 1.河北省胸科医院检验科,河北 石家庄 050041;2.河北省石家庄市第五医院检验科,河北 石家庄 050021;
    3.河北省胸科医院结核科,河北 石家庄 050041;4.河北省胸科医院肾内科,河北 石家庄 050041
  • 出版日期:2016-07-25 发布日期:2016-08-11
  • 作者简介:郑立恒( 1979- )男,河北辛集人,河北省胸科医院主 管检验师,医学硕士,从事临床检验学研究。

Valueanalysisof3methodsinthediagnosisoftuberculouspleurisy

  1. 1.Department of Clinical Laboratory, Chest Hospital of Hebei Province, Shijiazhuang 050041, China;
    2.Department of Clinical Laboratory, the Fifth Hospital of Shijiazhuang City, Hebei Province,
    Shijiazhuang 056000, China; 3.Department of Internal Medicine, Chest Hospital of Hebei
    Province,Shijiazhuang 050041, China; 4.Department of Tuberculosis, Chest
    Hospital of Hebei Province, Shijiazhuang 050041, China
  • Online:2016-07-25 Published:2016-08-11

摘要: [摘要] 目的 评价胸水 XpertMTB / RIF 系统、腺苷脱氨酶( adenosinedeaminase , ADA )活性检测和外周血结
核分枝杆菌感染 T 细胞斑点试验( T-SPOT.TB )在结核性胸膜炎诊断中的价值。方法 回顾性分析河北省胸科医
院确诊的 109 例结核性胸膜炎患者的胸水 XpertMTB / RIF 系统检测结果、 ADA 活性以及外周血 T-SPOT.TB 检
查结果。结果 XpertMTB / RIF 系统与 ADA 活性检测法、 T-SPOT.TB 法、 ADA 活性检测联合 T-SPOT.TB 法差
异有统计学意义( P <0.05 ),但 ADA 活性检测法、
T-SPOT.TB 法、 ADA 活性检测联合 T-SPOT.TB 法三者之间
差异无统计学意义( P >0.05 )。结论 由于结核性胸水多为刺激产生,含有结核分枝杆菌的胸水很少,
XpertMTB /
RIF 系统应用在胸水检测中阳性率低,对结核性胸膜炎的诊断意义有限; ADA 活性和 T-SPOT.TB 检测阳性率高,
联合检测诊断效果更好,对结核性胸膜炎有重要的辅助诊断价值。

关键词: 结核, 胸膜, 胸水, 诊断

Abstract: [
Abstract ] Objective ToevaluatetheclinicalvalueofXpert MTB / RIFassay , levelof
adenosinedeaminase ( ADA ) methodandT-SPOT.TBmethodindiagnosisoftuberculouspleurisy.
Methods Atotalof109patientswithtuberculouspleurisywereenrolledinthisretrospective
study , andtheirpleuraleffusionweregivenXpertMTB
/ RIFassayandthelevelsofADA were
measured.The whole blood was detected by T-SPOT.TB method.Results There were
significantdifferencesin MTB / RIF Xpertsystem and ADA activity detection method , T-
SPOT.TBmethod , ADAactivitydetectioncombinedT-SPOT.TB method ( P <0.05 ) .There
weresignificantdifferencesinADA activityassay , T-SPOT.TB assay , ADA activityassay
combinedwithT-SPOT.TB method ( P >0.05 ) .Conclusion Becausethetuberculouspleural
effusionisstimulatedandmycobacteriumtuberculosiscontainsverylittlepleuraleffusion , the
positiverateoftheapplicationofXpertMTB / RIFsysteminhydrothoraxdetectionislow , the
significanceinthediagnosisoftuberculouspleurisybythismethodislimited.Thepositiverateof
ADAactivityandT-SPOT.TBtestishigh , andthejointdetectionanddiagnosiseffectisbetter  indicatingADAactivityandT-SPOT.TBtestarevaluablemethodsindiagnosisoftuberculous
pleurisy.

Key words: tuberculosis, pleural, hydrothorax, diagnosis