河北医科大学学报

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2种手术方式治疗早期乳腺癌的远期效果研究

  

  1. 河北省石家庄市第三医院普外科,河北 石家庄 050011
  • 出版日期:2016-05-25 发布日期:2016-05-20
  • 作者简介:苗江雨( 1979- ),男,河北石家庄人,河北省石家庄 市第三医院主治医师,医学硕士,从事普外科疾病诊治研究。

The long-term therapeutic effect of two operation methods on early breast cancer patients#br#

  1. Department of General Surgery, the Third Hospital of Shijiazhuang City, Hebei Province, Shijiazhuang 050011, China
  • Online:2016-05-25 Published:2016-05-20

摘要: [摘要] 目的 比较乳腺区段切除术并腋淋巴结清扫与改良根治术治疗临床 Ⅰ 、 Ⅱ 乳腺癌的远期临床效果。
方法 临床 Ⅰ 、 Ⅱ 乳腺癌患者 100 例,根据治疗方法分为乳腺癌改良根治术(对照组)及乳腺区段切除并腋淋巴结清
扫术(观察组)各 50 例。比较 2 组术后生存率、转移率、复发率、体力状况评分以及生存质量评分。结果 治疗后 2
组 1 年及 3 年生存率、复发率以及转移率比较差异均无统计学意义( P >0.05 ); 2 组体力状况评分均呈增高趋势,
观察组增高幅度大于对照组,
2 组生存质量评分均呈下降趋势,观察组降低幅度小于对照组,组间、不同时点间、组
间·不同时点间交互作用差异均有统计学意义( P <0.05 )。结论 乳腺区段切除并腋淋巴结清扫治疗早期乳腺癌
远期疗效优于乳腺癌改良根治术,值得临床推广。

关键词: 乳腺肿瘤, 乳房切除术, 淋巴结切除术

Abstract: [ Abstract ] Objective To analysisthelong-term clinicalresults of modified radical
mastectomyversuspartialmastectomywithaxillarylymphnodedissectiononphaseⅠ , Ⅱbreast
cancerpatients.Methods BreastcancerpatientsinphaseⅠ , Ⅱ ( n =100 ) weredividedintotwo
groups : modifiedradicalmastectomygroup (
controlgroup , n =50 ) andpartialmastectomywith
axillarylymphnodedissectiongroup ( observationgroup , n =50 ) .Survivalrate , transferrate ,
recurrentrate , performancestatusandscoresofsurvivalqualitybetweenthetwogroupswere
compared.Results Therewerenosignificantdifferencebetweenthetwogroupsintermsof
survivalrate , transferrateandrecurrentratebetweenthetwogroups ( P >0.05 ) .Thereisan
increasingtrendintheperformancestatusinthetwogroups , andtheincreasedegreein
observationgroupsishigherthancontrolgroup.Scoresofqualityoflifeofthe2groupswereall
decreased.Theobservationgroupwaslowerthanthecontrolgroupandthedescendrangeinthe
observationgroupissmallerthancontrolgroup.Therewerestatisticallysignificantdifferencesin
theinteractionofthetwogroupsatthesametimebetweenthetwogroups , thedifference
betweenthetwogroups , andthedifferencebetweenthetwogroups ( P <0.05 ) .Conclusion
Breastsectionexcisionandaxillarylymphnodedissectioninthetreatmentofearlybreastcancer
issuperiortobreastcancermodifiedradicalmastectomy.Itisworthyofclinicalapplication.

Key words: breast neoplasms, mastectomy, lymph node excision