河北医科大学学报

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伴颅内外动脉狭窄的短暂性脑缺血发作患者多导睡眠图分析

  

  1. 1.河北省沧州市中心医院神经内三科,河北 沧州 061001;2.河北省沧州市中心医院神经内四科,河北 沧州 061001
  • 出版日期:2016-06-25 发布日期:2017-01-16
  • 作者简介:刘洁琼( 1982- ),女,河北沧州人,河北省沧州市 中心医院主治医师,医学硕士,从事神经内科疾病诊治研究。
  • 基金资助:
    沧州市科学技术研究与发展计划( 141302085 )

Analysis of polysomnography of transient ischemic attack patients with intra-and extracranial largeartery stenosis

  1. 1.Department of Neurology Ⅲ, Cangzhou Central Hospital, Hebei Province, Cangzhou 061001, China;
    2.Department of Neurology Ⅳ, Cangzhou Central Hospital, Hebei Province, Cangzhou 061001, China
  • Online:2016-06-25 Published:2017-01-16

摘要: [摘要] 目的 探讨伴颅内外动脉狭窄的短暂性脑缺血发作( transientischemicattack , TIA )患者多导睡眠图
的特点。方法 56 例 TIA 患者分为伴颅内外动脉狭窄者 25 例( A 组),不伴有颅内外动脉狭窄者 31 例( B 组),进行
临床评估、汉密尔顿焦虑量表( HamiltonAnxietyScale , HAMA )、汉密尔顿抑郁量表( HamiltonDepressionScale ,
HAMD )、匹兹堡睡眠质量指数( PittsburghSleepQualityIndex , PSQI )、多导睡眠图( polysomnography , PSG )和影
像学检查比较。结果 2 组患者睡眠障碍发生率、 PSQI 总分和阻塞性睡眠呼吸暂停综合征发生率差异无统计学意
义( P >0.05 )。 A 组总睡眠时间、非快速眼动睡眠(
non-rapideyemovement , NREM )时间、 N3 / NREM 短于 B 组,
睡眠效率低于 B 组,觉醒时间、 N2 / NREM 长于 B 组,差异均有统计学意义( P <0.05 )。 2 组总记录时间、睡眠潜伏
期、快速眼动睡眠(
rapideyemovement , REM )潜伏期、 REM 时间、 N1 / NREM 差异均无统计学意义( P >0.05 )。结
论 伴颅内外动脉狭窄的 TIA 患者总睡眠时间缩短,觉醒时间延长,睡眠效率降低,总 NREM 期时间缩短, N2 /
NREM 睡眠时间延长, N3 / NREM 睡眠时间明显缩短,睡眠质量更差。

关键词: 脑缺血发作, 短暂性, 颈动脉狭窄, 多导睡眠描记术

Abstract: Abstract]  ObjectiveTo assess the characteristic of transient ischemic attack patients with intraand extracranial largeartery stenosis. MethodsFiftysix cases of transient ischemic attack patients were divided into two groups, twentyfive cases with intra and extracranial largeartery stenosis(group A), and thirtyone cases without intra and extracranial largeartery stenosis(group B). All the participants were examined by clinical assess, Hamilton Anxiety Scale(HAMA), Hamilton Depression Scale(HAMD), Pittsburgh Sleep Quality Index(PSQI), polysomnography(PSG), imaging examination. The data were compared between the two groups. ResultsThere was no statistical difference between the two groups in terms of the incidence rate of sleep disorder,PSQI scores and the incidence rate of obstructive sleep apnea syndrome(P>0.05). Total sleep time, total nonrapid eye movement(NREM) time and N3/NREM in group A were shorter than that in group B, and sleep efficiency in group A were lower than that in group B, whereas wakening time and sleep time of N2/NREM in group A were longer than that in group B(P<0.05). But there was no statistical difference between the two groups in terms of total recording time, sleep latency, rapid eye movement(REM) latency, REM time, and N1/NREM(P>0.05). ConclusionTIA patients with intraand extracranial largeartery stenosis were more prone to shorter total sleep time, longer wakening time, lower sleep efficiency, shorter total NREM time, longer N2/NREM, shorter N3/NREM, and lower sleep quality.

Key words: ischemic attack, transient, carotid stenosis, polysomnography